منابع مشابه
From bench to bedside
Because the microcirculation has emerged as an important reanimation target, appropriate methods to monitor the microcirculatory function are crucial. Several teams have now succeeded in crossing this bridge from bench to bedside, but the choice of the tissues of interest remains a debate. The potential accessible vascular beds that doctors could use in reanimation strategies and the relationsh...
متن کاملFrom Bench to Bedside
Since the initial experiments nearly a decade ago, remarkable progress has been made in the field of vascular gene transfer, and trials with human subjects already are under way. The potential of vascular wall gene transfer as therapy for various vascular diseases is considerable.1,2 The purpose of this review is 2-fold: (1) to delineate the methods and principles underlying vascular gene trans...
متن کاملBench-to-bedside review: Metabolism and nutrition
Acute kidney injury (AKI) develops mostly in the context of critical illness and multiple organ failure, characterized by alterations in substrate use, insulin resistance, and hypercatabolism. Optimal nutritional support of intensive care unit patients remains a matter of debate, mainly because of a lack of adequately designed clinical trials. Most guidelines are based on expert opinion rather ...
متن کاملNutrition: From Bench to Bedside
The nutritional health in the world is one of the most pressing issues facing different countries today. International organizations like FAO and WHO suggest that there is an improvement of the nutritional situation in Asia and Latin America, though a deterioration in Sub-Saharan Africa does exist. As regards Europe and USA, we are living in the era of " overnutrition. " Unfortunately, the situ...
متن کاملCXCR2: From Bench to Bedside
Leukocyte recruitment to sites of infection or tissue damage plays a crucial role for the innate immune response. Chemokine-dependent signaling in immune cells is a very important mechanism leading to integrin activation and leukocyte recruitment. CXC chemokine receptor 2 (CXCR2) is a prominent chemokine receptor on neutrophils. During the last years, several studies were performed investigatin...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 2010
ISSN: 1078-8956,1546-170X
DOI: 10.1038/nm0410-387